Multiple whole-genome alignments without a reference organism
نویسندگان
چکیده
منابع مشابه
Whole Genome Alignments Based On Local Alignments
Given the genomes (DNA) of two related species, one of the whole genome alignment tasks is to locate regions on the genomes that possibly contain genes conserved over the two species. Most of the existing whole genome alignment software tools, MUMmer (Delcher et al., 2002; Kurtz et al., 2004), MaxMincluster (Wong et al., 2004), and MSS (Chan et al., 2004), generate Maximal Unique Matches (MUMs)...
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IINTRODUCTION It was not until closely related organism genomes have been sequenced that people start to think about aligning genomes and chromosomes instead of short DNA sequences. There are a large number of algorithms and methods developed for sequence alignment, in order to find conserved sequences across species. Smith & Waterman and Needleman & Wunsch algorithms are among the most popular...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2009
ISSN: 1088-9051
DOI: 10.1101/gr.081778.108